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Alum . White lead PbCO3 Inorganic lead salt Chronic exposure Cosmetics . Cosmetics . ( ) ( 0,3 % ) Chronic exposure . . 5-15 % . . 90 % . 10-25 / Asymptomatic . renal insufficiency Renal failure . Dyslexia Mental retardation . 20 / 45 / Hospitalized . 20- 44 / .
: : ( -SH ) ( ) Lead combined with sulfhydryl of biological compounds . . . . .
( 1 ) Chronic Exposure ( ) . 10 100 / . Encephalopathy Seizures / Permanent mental retardation ( 100 / ) . Headache Anorexia Abdominal pain Nausea Vomiting Diarrhea Chronic constipation ****llic taste Hepatic injury Anemia Muscle & joint pain Hypertension Growth hormone Catecholamines Hyperuricemia Gout Weight loss Weakness & malaise Fatigue Irritability .
( 2 ) Acute exposure ( ) . Anorexia Vomiting Malaise Convulsion Permanent brain damage due to increased intracranial pressure Renal injury Acute syndrome of hepatic injury Hemolysis .
: 1/2t Half life . HRYHORCZUK et.al,1985 27 44 . 7-63 29 . 5-6 . . 003 / ( 03 / ) 5 011 / ( 11 / ) 022 / ( 22 / ) . . .
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